kez biosolutions – Polyketides from the bioreactor
The Future of Polyketide Research
With our revolutionary kezbio platform, we insert new chemical functions on the polyketide backbone in exact locations, creating unprecedented variability in this active molecule class.
We are a young company and work on the edge of the unknown. Technological and entrepreneurial challenges are faced with broad knowledge, many years of experience and unbridled creativity. We draw on a strong network to realize our vision: new, innovative and sustainable medicines from the bioreactor.
Our applications.
We Create New-To-Nature Molecules
Our solutions.
Customized Polyketides from the Bioreactor
We develop novel candidates for academic basic research or your drug development pipeline.
We are currently working on our prototype and creating an erythromycin-based drug library as a proof-of-concept. Subsequently, our initial offering will be a customized start-up package of our KEZ® substrates, plasmid systems and strains for specific derivatization of any polyketide scaffold. If you are interested in our technology and have a lead structure in mind, please contact us so that we can expand our offer according to your needs at an early stage.
Our technology.
Innovative Platform for Novel Active Ingredients
We develop new active ingredients through engineering the polyketide biosynthesis. Our kezbio platform offers unprecedented and flexible possibilities for the chemical modification of polyketide scaffolds. The core is a pair of different KEZ® substrates and our patented (pending and published) enzyme Selectase®.
We are revolutionizing the lead structure optimization of small molecule active substances of the polyketide class and hold out the prospect of a wide range of applications. The substances are produced sustainably in the bioreactor and remain comparatively inexpensive thanks to the robust, natural processes.