kez.biosolutions – COVALENT DRUG DISCOVERY.
Drug discovery at the intersection of metabolism, fibrosis and oncology.
Building next-generation small molecules that redefine metabolic medicine and biology of aging.
Every breakthrough medicine starts with the right molecule.
We design next-generation small molecules to unlock the full therapeutic potential of clinically validated and emerging targets. For decades, many disease-relevant targets were considered beyond the reach of traditional drug discovery. At kezbio, we are committed to challenge this limitation.
We engineer precision covalent drugs that selectively modulate disease-driving proteins.
SELECTIVITY
Novel covalent chemistry delivers highly selective target engagement for improved precision and safety.
EFFICACY
Precision chemistry enables sustained target engagement, maximizing efficacy while minimizing systemic drug exposure.
Physiology
Durable target engagement sustains therapeutic activity beyond systemic drug exposure, potentially enabling less frequent dosing.
CHEMO-ENZYMATIC PLATFORM.
Fast-track to novel drug candidates.
The challenge is no longer finding the right target – it is designing the right molecule. For many targets, existing molecules lack the selectivity, potency, or developability needed to become transformative medicines. At kezbio, our proprietary IFE-platform removes these limits: new chemical space, synthesizable by design, and target-validated results within weeks – powered by Selectase®, our proprietary enzyme family.
A grid representing chemical space, where every node the line reaches turns teal, ending in a Novel Candidate target lock, inside a softly elevated frame.
Our Partners.
Trusted by our ecosystem.
UNDISCLOSED
TECHNOLOGY MADE IN EUROPE.
Funding
We raised a total of €3M+ in dulitive and non-dilutive funding to date.
ProFIT Brandenburg
Funded by the European Union and the State of Brandenburg: ProFIT Brandenburg project for the development of a biotechnological platform for the discovery of novel covalent ligands (TCLs).
Gefördert aus Mitteln der Europäischen Union und des Landes Brandenburg:
ProFIT-Brandenburg-Projekt zu Entwicklung einer Biotechnologischen Plattform zur Entdeckung neuer kovalenter Liganden (TCLs).
Brandenburger Innovationsfachkräfte
Funded by the European Union and the State of Brandenburg: project supporting working students, aimed at stabilizing and optimizing enzyme systems for the in-vitro production of small molecules.
Gefördert aus Mitteln der Europäischen Union und des Landes Brandenburg:
Projekt zur Förderung von Werksstudierenden mit dem Ziel der Stabilisierung und Optimierung von Enzymsystemen für die in-vitro Produktion von Kleinmolekülen.
Zentrales Innovationsprogramm Mittelstand (ZIM)
kezbio receives funding from the Central Innovation Programme for SMEs (ZIM) to research the production of natural-product building blocks for drug libraries in bacteria.
kezbio erhält Mittel aus dem Zentralen Innovationsprogramm Mittelstand (ZIM) für die Erforschung der Produktion von Naturstoff-Bausteinen für Wirkstoffbibliotheken in Bakterien.